1945 in comics

European publications

 * March 30: first appearance of Suske en Wiske by Willy Vandersteen, in De Nieuwe Standaard, mistitled Rikki en Wiske.
 * El Caballero Negro by Guillermo Sánchez Boix

Year overall

 * Real Screen Funnies debuts with a Spring 1945 cover date. The title changes to Real Screen Comics with the second issue (Summer 1945) and features The Fox and the Crow and other Columbia-licensed funny animal characters. - (National Comics)

January

 * All-Winners Comics (1941 series) #14 - Timely Comics
 * Captain America Comics (1941 series) #44 - Timely Comics
 * Marvel Mystery Comics (1939 series) #61 - Timely Comics
 * Sub-Mariner Comics (1941 series) #15 - Timely Comics

March

 * Captain America Comics (1941 series) #45 - Timely Comics
 * Marvel Mystery Comics (1939 series) #62 - Timely Comics

April

 * All-Winners Comics (1941 series) #15 - Timely Comics
 * Captain America Comics (1941 series) #46 - Timely Comics
 * Human Torch (1940 series) #18 - Timely Comics
 * Marvel Mystery Comics (1939 series) #63 - Timely Comics
 * Sub-Mariner Comics (1941 series) #16 - Timely Comics
 * U.S.A. Comics (1941 series) #15 - Timely Comics

June

 * Captain America Comics (1941 series) #47 - Timely Comics
 * Marvel Mystery Comics (1939 series) #64 - Timely Comics

July

 * All-Winners Comics (1941 series) #16 - Timely Comics
 * Captain America Comics (1941 series) #48 - Timely Comics
 * Human Torch (1940 series) #19 - Timely Comics
 * Marvel Mystery Comics (1939 series) #65 - Timely Comics
 * U.S.A. Comics (1941 series) #16 - Timely Comics

August

 * Captain America Comics (1941 series) #49 - Timely Comics

September

 * Marvel Mystery Comics (1939 series) #66 - Timely Comics

October

 * Captain America Comics (1941 series) #50 - Timely Comics
 * Human Torch (1940 series) #20 - Timely Comics
 * Sub-Mariner Comics (1941 series) #17 - Timely Comics
 * U.S.A. Comics (1941 series) #17 - Timely Comics

November

 * All-Winners Comics (1941 series) #17 - Timely Comics
 * Human Torch (1940 series) #21 - Timely Comics
 * Marvel Mystery Comics (1939 series) #67 - Timely Comics

December

 * Captain America Comics (1941 series) #51 - Timely Comics

First issues by title

 * Patsy Walker (Timely Comics)