Roanoke

Roanoke may refer to:


 * Roanoke tribe, Carolina Algonquian-speaking tribe in eastern North Carolina
 * Roanoke Colony, a former English colony that mysteriously disappeared
 * Roanoke Island, location of the Roanoke colony in present-day North Carolina
 * Roanoke River, flowing through Virginia and North Carolina and emptying into Albemarle Sound near Roanoke Island
 * Roanoke Valley, a part of the Great Appalachian Valley near the headwaters of the Roanoke River in Virginia
 * Roanoke, Alabama
 * Roanoke, Georgia
 * Roanoke, Illinois
 * Roanoke, Indiana
 * Roanoke, Louisiana
 * Roanoke, Missouri
 * Roanoke, Texas
 * Roanoke, Virginia, the largest US city named Roanoke
 * Roanoke County, Virginia
 * Roanoke, West Virginia
 * Roanoke Rapids, North Carolina
 * Randolph, Virginia, formerly called Roanoke

Other references

 * USS Roanoke, various USN vessels named Roanoke
 * Roanoke (ship), an American ship (1892–1905)
 * Roanoke College, a private liberal arts college located in Salem, Virginia
 * Neo Roanoke, a fictional character in Mobile Suit Gundam SEED Destiny, an anime series
 * Roanoke Building, a building in Chicago, Illinois
 * American Horror Story: Roanoke, the sixth season of the FX horror anthology television series American Horror Story
 * Roanoke Station (disambiguation)