Really & Truly was a strip by Grant Morrison and Rian Hughes, part of 2000 AD's so-called Summer Offensive of 1993. It featured the adventures of two women (well, probably girls – all women were girls in the 1990s) called Really Something and Truly Amazing, who are tasked with delivering a consignment of drugs. Their passengers are cosmonaut Johnny Zhivago and beat poet Scuba Trooper, and they are being chased by government narcotics agent Captain Nice and mobster Boss Buddah.
There is a rumour being bandied about on the internet (what else is the internet for?) that Morrison wrote this in one night after getting high on ecstasy, but given that a lie can run round the world before the truth has got its boots on this should be taken with a pinch of salt. Rian Hughes hasn't claimed to be inspired by anything less ethereal than the celestial partnership of the Muse and his own genius while producing the artwork.